Chen W, Chen X
Department of Stomatology, Tongji Hospital, Tongji Medical University, Wuhan.
J Tongji Med Univ. 1996;16(1):55-7. doi: 10.1007/BF02889047.
Presented in this paper is a clinico-pathological report of 11 cases of gingival fibromatosis. Of the 11 patients in our series, 2 cases (18.2%) with family history began to have symptom from age of 3, which is manifested by the involvement of whole gum. 9 patients (81.8%), for which the etiology was unknown, had onset of the disease at the periods of deciduous dentition, mixed dentition or permanent dentition, with localized or overall involvement of gingiva. The disease is characterized by diffuse or localized proliferation of gum. Microscopically, the proliferating gum tissue revealed well-developed fibrotic structure with few cells; and the fibers were densely arranged without clear boundary. The fibrotic tissues showed a diminishing of blood vessels and the infiltration of inflammatory cells is not conspicuous.
本文呈现了11例牙龈纤维瘤病的临床病理报告。在我们的11例患者系列中，2例（18.2%）有家族史，从3岁开始出现症状，表现为全牙龈受累。9例（81.8%）病因不明，在乳牙列、混合牙列或恒牙列期发病，牙龈局部或全部受累。该病的特点是牙龈弥漫性或局限性增生。显微镜下，增生的牙龈组织显示纤维结构发育良好，细胞较少；纤维密集排列，边界不清。纤维化组织血管减少，炎症细胞浸润不明显。
