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沙眼衣原体和解脲脲原体感染所致不孕症的研究

[Study on infertility caused by infections of Chlamydia trachomatis and ureaplasma urealyticum].

作者信息

Xiang Y, Chen Q

机构信息

Department of Microbiology, Wannan Medical College, Anhui Wuhu.

出版信息

Zhonghua Fu Chan Ke Za Zhi. 1996 Apr;31(4):223-5.

PMID:8758778
Abstract

OBJECTIVE

To explore the effects of chlamydia trachomatis (CT) and ureaplasma urealyticum (UU) infections on male and female infertility.

METHODS

Samples from cervical canal or male urethra of 1198 infertile patients (599 couples) were studied and from 167 normal fertile men and women served as control. The fluorescent monoclonal antibody technique and the culture method were used for CT and UU assays respectively.

RESULTS

The positive rates of CT and UU infections in infertile group were 25.5% (306/1 198) and 35.9% (167/1 198) respectively, while 6.6% (11/167) and 15.6% (26/167) in the control group respectively. There were significant differences between the 2 groups (P < 0.01). After treatment of positive patients, the pregnancy rates were higher in those patients became negative than that in patients remained positive (P < 0.01).

CONCLUSION

The CT and UU infections were one of the factors causing infertility.

摘要

目的

探讨沙眼衣原体(CT)和解脲脲原体(UU)感染对男性和女性不孕的影响。

方法

对1198例不孕患者(599对夫妇)的宫颈管或男性尿道样本进行研究,并以167例正常生育的男性和女性作为对照。分别采用荧光单克隆抗体技术和培养法对CT和UU进行检测。

结果

不孕组CT和UU感染阳性率分别为25.5%(306/1198)和35.9%(167/1198),而对照组分别为6.6%(11/167)和15.6%(26/167)。两组之间存在显著差异(P<0.01)。阳性患者治疗后,转阴患者的妊娠率高于仍为阳性的患者(P<0.01)。

结论

CT和UU感染是导致不孕的因素之一。

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