Kopp B, Mattler U, Goertz R, Rist F
Humboldt University at Berlin, Department of Psychology, Hausvogteiplatz, Germany.
Electroencephalogr Clin Neurophysiol. 1996 Jul;99(1):19-27. doi: 10.1016/0921-884x(96)95617-9.
Motor inhibition and its correlates in the event-related potential (ERP) are often studied in go/nogo tasks. However, go and nogo trials differ in their motor and their attentional requirements, rendering an interpretation of corresponding changes in ERP components difficult. As an alternative strategy to study motor inhibition, a hybrid choice-reaction go/nogo procedure involving selective response priming was used. Eighteen subjects performed the task. Response time (RT) and error measures as well as the lateralized readiness potential (LRP) indicated that responses were primed by flanker stimuli that were associated with one of the two possible responses. In nogo trials, selective response priming influenced the N2 amplitude whereas the P3 amplitude was unaffected. Because the N2 appeared irrespective of whether an erroneous response was correctable (in go trials) or not (in nogo trials), we conclude that the N2 reflects either the detection or the inhibition of an inappropriate tendency to respond.
运动抑制及其在事件相关电位（ERP）中的相关因素通常在“执行/不执行”任务中进行研究。然而，执行和不执行试验在运动和注意力要求方面存在差异，这使得对ERP成分相应变化的解释变得困难。作为研究运动抑制的一种替代策略，采用了一种涉及选择性反应启动的混合选择反应“执行/不执行”程序。18名受试者完成了该任务。反应时间（RT）、错误测量以及侧化准备电位（LRP）表明，与两种可能反应之一相关的侧翼刺激启动了反应。在不执行试验中，选择性反应启动影响N2波幅，而P3波幅不受影响。由于无论错误反应是否可纠正（在执行试验中）或不可纠正（在不执行试验中）N2波都会出现，我们得出结论，N2反映了对不适当反应倾向的检测或抑制。
