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革兰氏阳性θ复制质粒中的位点特异性重组

Site-specific recombination in gram-positive theta-replicating plasmids.

作者信息

Alonso J C, Ayora S, Canosa I, Weise F, Rojo F

机构信息

Centro Nacional de Biotecnología, C.S.I.C., Campus Universidad Autónoma de Madrid, Cantoblanco, Spain.

出版信息

FEMS Microbiol Lett. 1996 Aug 15;142(1):1-10. doi: 10.1111/j.1574-6968.1996.tb08399.x.

Abstract

This review summarises current information on the site-specific recombinases encoded by the plasmids of the Gram-positive bacteria that have low guanine and cytosine content in their DNA. It focuses on the peculiar biological features of the recombination systems encoded by the theta-replicating plasmids and compares them with the site-specific recombinases encoded by transposons or plasmids originally isolated from Gram-negative bacteria.

摘要

本综述总结了关于革兰氏阳性菌质粒所编码的位点特异性重组酶的当前信息,这些细菌的DNA中鸟嘌呤和胞嘧啶含量较低。它着重于θ复制质粒所编码的重组系统的独特生物学特性,并将它们与最初从革兰氏阴性菌中分离出的转座子或质粒所编码的位点特异性重组酶进行比较。

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