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脑室周围白质软化症早产儿的视力损害——与脑成像相关的视觉、认知和神经儿科特征

Visual impairment in preterm children with periventricular leukomalacia--visual, cognitive and neuropaediatric characteristics related to cerebral imaging.

作者信息

Jacobson L, Ek U, Fernell E, Flodmark O, Broberger U

机构信息

Department of Ophthalmology, Huddinge Hospital, Sweden.

出版信息

Dev Med Child Neurol. 1996 Aug;38(8):724-35. doi: 10.1111/j.1469-8749.1996.tb12142.x.

DOI:10.1111/j.1469-8749.1996.tb12142.x
PMID:8761168
Abstract

Thirteen preterm children, aged 4 to 14 years, with visual impairment due to periventricular leukomalacia (PVL) were evaluated for visual function, intellectual level, cognitive profile and motor function. Their visual impairment was characterized by low acuity, crowding, visual field defects and ocular motility disturbances. Their cognitive profile was uneven, often with considerably higher scores on verbal than on visual-spatial tasks. Nine children had normal intelligence, three had mild mental retardation and one had severe mental retardation. In all the children, visual impairment was complicated by visual perceptual difficulties, accounting for their greater visual handicap than would be expected from their visual acuities and strabismus alone. Though CT or MRI revealed bilateral PVL in all the children, six had no motor impairment consistent with cerebral palsy, which is an unexpected finding.

摘要

对13名年龄在4至14岁之间、因脑室周围白质软化症(PVL)导致视力障碍的早产儿童进行了视觉功能、智力水平、认知特征和运动功能评估。他们的视力障碍表现为视力低下、拥挤现象、视野缺损和眼球运动障碍。他们的认知特征不均衡,在语言任务上的得分通常比视觉空间任务高得多。9名儿童智力正常,3名有轻度智力障碍,1名有重度智力障碍。在所有儿童中,视力障碍都伴有视觉感知困难,这使得他们的视觉障碍比仅由视力和斜视所预期的更为严重。尽管CT或MRI显示所有儿童均有双侧PVL,但有6名儿童没有与脑瘫相符的运动障碍,这是一个意外发现。

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