Kristensen C A, Nozue M, Boucher Y, Jain R K
Edwin L Steele Laboratory, Harvard Medical School, Massachusetts General Hospital, Boston 02114, USA.
Br J Cancer. 1996 Aug;74(4):533-6. doi: 10.1038/bjc.1996.397.
Tumour necrosis factor-alpha (TNF-alpha) reduced the interstitial fluid pressure (IFP) to 54-64% (P < 0.05) and the mean arterial blood pressure (MABP) to 70% (P < 0.01) of control values after 5 h in three human melanoma tumour lines transplanted to nude mice.
在移植到裸鼠体内的三个人类黑色素瘤肿瘤系中,肿瘤坏死因子-α(TNF-α)在5小时后将间质液压力(IFP)降至对照值的54 - 64%(P < 0.05),并将平均动脉血压(MABP)降至对照值的70%(P < 0.01)。