[Severe contact dermatitis caused by mephenesin].
作者信息
Bachmeyer C, Blum L, Fléchet M L, Duriez P, Cabane J, Imbert J C
机构信息
Service de Médecine Interne, Hôpital Hôtel-Dieu, Paris.
出版信息
Ann Dermatol Venereol. 1996;123(3):185-7.
INTRODUCTION
Mephenesin is a muscle relaxant, mostly applied locally in trauma. It is a component of Traumalgyl cream in association with phenylbutazone. Contact dermatitis due to mephenesin is exceptional.
CASE REPORT
We report here a case of a woman who developed after application of Traumalgyl cream purpuric dermatitis, erythema multiforme-like and urticarial lesions. Patch-tests were strongly positive (+ + +) for both Traumalgyl cream and mephenesin and (+) for phenylbutazone. Improvement of the lesions was observed within 3 weeks.
DISCUSSION
Physicians must be aware of the risk of severe contact dermatitis after application of products including mephenesin because of their widely prescription.
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