Collet E, Lacroix M, Boulitrop Morvan C, Dalac S, Sallin J, Lambert D
Service de Dermatologie, Hôpital du Bocage, Dijon.
Ann Dermatol Venereol. 1993;120(12):892-3.
Bufexamac is an anti-inflammatory agent used as topical treatment of various pruritic diseases. Since it was put on the market, this product has been blamed for the occurrence of contact dermatitis (eczema, urticaria) and, rarely, severe toxicodermia. We report a case of severe contact dermatitis developed after application of bufexamac (Parfenac) cream. Patch-tests performed two months after the acute phase were positive (+ + +) for both Parfenac cream and bufexamac.
丁苯羟酸是一种抗炎药，用于局部治疗各种瘙痒性疾病。自该产品上市以来，一直被指责会引发接触性皮炎（湿疹、荨麻疹），极少数情况下会引发严重的中毒性表皮坏死松解症。我们报告了一例使用丁苯羟酸（帕芬那克）乳膏后发生严重接触性皮炎的病例。急性期两个月后进行的斑贴试验显示，帕芬那克乳膏和丁苯羟酸的结果均为强阳性（ + + +）。
