Salmon-Ehr V, Estève E, Cambie M P, Serpier H, Kalis B
Service de Dermatologie, Hôpital Robert-Debré, Reims.
Ann Dermatol Venereol. 1996;123(3):194-5.
We report one case of melanoma cutaneous metastases strictly localized on a skin graft donor site distant from the tumor site.
A patient with a shoulder melanoma was treated by surgery. A split-thickness skin graft was taken from a thigh to cover the raw area. Six months later, nodular cutaneous metastases strictly localized on the skin graft donor site appeared.
Physiopathology of those lesions is unknown. Hyaluronic acid is increased in granulation tissue and could be chimiotactic for melanoma cells.
我们报告一例皮肤黑色素瘤转移灶严格局限于远离肿瘤部位的皮肤移植供区的病例。
一名肩部黑色素瘤患者接受了手术治疗。从大腿取了一张中厚皮片来覆盖创面。六个月后,在皮肤移植供区出现了严格局限的结节性皮肤转移灶。
这些病变的病理生理学尚不清楚。肉芽组织中的透明质酸增加,可能对黑色素瘤细胞具有趋化作用。