[Preparation of beta-1,3-glucan synthase and its application to the screening of antifungal antibiotics].

beta-1,3-glucan synthase was obtained as a particulate fraction from cell-free extracts prepared after mechanical breakage cells of Candida albicans. Some properties of the glucan synthase were investigated. Using it as a target for screening for novel antifungal compounds, we obtained strains whose products showed differential enzyme inhibition.