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[Preparation of beta-1,3-glucan synthase and its application to the screening of antifungal antibiotics].

作者信息

Zheng D, Zhang J, Song Y, Song D

机构信息

State Key Laboratory of Microbial Resources, Academia Sinica, Beijing.

出版信息

Wei Sheng Wu Xue Bao. 1996 Feb;36(1):73-5.

PMID:8762475
Abstract

beta-1,3-glucan synthase was obtained as a particulate fraction from cell-free extracts prepared after mechanical breakage cells of Candida albicans. Some properties of the glucan synthase were investigated. Using it as a target for screening for novel antifungal compounds, we obtained strains whose products showed differential enzyme inhibition.

摘要

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