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[结核硬脂酸测定用于诊断结核杆菌培养阴性的结核性脑膜炎]

[Determination of tuberculostearic acid for diagnosis of tuberculous meningitis with negative culture of tubercle bacillus].

作者信息

Kang J, Bao M, Liang J

机构信息

General Hospital of Shenyang PLA.

出版信息

Zhonghua Jie He He Hu Xi Za Zhi. 1995 Dec;18(6):340-3, 382.

PMID:8762491
Abstract

Tuberculostearic acid, a structural component of Mycobacterium tuberculosis, was identified by gas chromatography in cerebrospinal fluid from 44 out of 59 patients with tuberculous meningitis. Tuberculostearic acid was found in the cerebrospinal fluid of 5 patients out of 112 with non-tuberculous meningitis or non-infectious disorders. The results showed the test had a sensitivity of 74.6% and a specificity of 95.9%. Detection of tuberculostearic acid in cerebrospinal fluid is a rapid, sensitive and specific test for tuberculous meningitis.

摘要

结核硬脂酸是结核分枝杆菌的一种结构成分,在59例结核性脑膜炎患者中,有44例患者的脑脊液经气相色谱法检测出结核硬脂酸。在112例非结核性脑膜炎或非感染性疾病患者中,有5例患者的脑脊液中发现了结核硬脂酸。结果显示该检测的灵敏度为74.6%,特异性为95.9%。脑脊液中结核硬脂酸的检测是一种用于结核性脑膜炎的快速、灵敏且特异的检测方法。

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Zhonghua Jie He He Hu Xi Za Zhi. 1995 Dec;18(6):340-3, 382.
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