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[一氧化氮长时间吸入治疗成人呼吸窘迫综合征1例]

[Prolonged inhalation of nitric oxide in adult respiratory distress syndrome in a case].

作者信息

Andresen M, Dougnac A, Castillo L, Carvallo C, Hernández G, Dagnino J, Díaz O

机构信息

Unidade de Tratamiento Intensivo Médico, Universidad Católica de Chile, Santiago.

出版信息

Rev Med Chil. 1996 Jan;124(1):94-102.

PMID:8762625
Abstract

Inhalation therapy with nitric oxide has been suggested as beneficial in the adult respiratory distress syndrome, however there are few reports of its prolonged use. We report a patient with a chronic lymphocytic leukemia that developed an adult respiratory distress syndrome with severe hypoxemia, refractory to conventional therapeutic measures, during the course of a septic shock. The patient received nitric oxide (19 ppm) improving arterial oxygen saturation and allowing the reduction of FiO2 to 40%. The patient died five days later due to a multiple organ failure.

摘要

一氧化氮吸入疗法已被认为对成人呼吸窘迫综合征有益,然而关于其长期使用的报道很少。我们报告了一名慢性淋巴细胞白血病患者,在感染性休克过程中发生了成人呼吸窘迫综合征并伴有严重低氧血症,对传统治疗措施无效。该患者接受了一氧化氮(19 ppm)治疗,动脉血氧饱和度得到改善,且能将吸入氧分数降至40%。患者五天后因多器官功能衰竭死亡。

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