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单侧支气管扩张症的手术治疗:结果与预后因素

Surgery for unilateral bronchiectasis: results and prognostic factors.

作者信息

Ashour M, Al-Kattan K M, Jain S K, Al-Majed S, Al-Kassimi F, Mobaireek A, Al-Hajjaj M, Al-Zear A

机构信息

Division of Thoracic Surgery, King Khalid University Hospital, Riyadh, Saudi Arabia.

出版信息

Tuber Lung Dis. 1996 Apr;77(2):168-72. doi: 10.1016/s0962-8479(96)90033-7.

Abstract

SETTING

King Khalid University Hospital referral centre for thoracic surgery, Riyadh, Saudi Arabia.

OBJECTIVE

To assess the results of surgery and factors influencing its outcome in patients with unilateral bronchiectasis.

DESIGN

A retrospective analysis of 40 patients with unilateral bronchiectasis who were operated upon consecutively at King Khalid Hospital, between July 1987 and May 1993.

RESULTS

Left-sided disease was seen in 60% (n = 24) and right-sided in 40% (n = 16) of the patients. The entire lung was involved in 30% of cases (n = 12). Of these, the left lung was totally involved in 22.5% (n = 9) and the right in 7.5% (n = 3). A lobectomy was performed on 21 patients, basal segmentectomy with preservation of apical segment on 7, and pneumonectomy on 12. There was no operative mortality in this series. Six patients (15%) developed postoperative complications, bleeding (n = 4) and prolonged air leak (n = 2). During an average follow-up period of 30.7 months (+/- 15.4 months), 29 patients (72.5%) were cured and the remaining 11 (27.5%) improved. No patients with Pseudomonas aeruginosa infection (n = 3) or obstructive airway disease (n = 5) were cured (P = 0.02 and P = 0.002 respectively).

CONCLUSION

Curative resection for selected patients with unilateral bronchiectasis can be performed safely with good results and low morbidity. Pseudomonas aeruginosa infection and obstructive airway disease have an adverse effect on postoperative cure.

摘要

背景

沙特阿拉伯利雅得市的哈立德国王大学医院胸外科转诊中心。

目的

评估单侧支气管扩张患者的手术结果及影响手术结局的因素。

设计

对1987年7月至1993年5月间在哈立德医院连续接受手术的40例单侧支气管扩张患者进行回顾性分析。

结果

60%(n = 24)的患者为左侧病变,40%(n = 16)为右侧病变。30%的病例(n = 12)整个肺脏均受累。其中,左肺完全受累的占22.5%(n = 9),右肺完全受累的占7.5%(n = 3)。21例行肺叶切除术,7例行保留尖段的基底段切除术,12例行全肺切除术。本系列中无手术死亡病例。6例患者(15%)出现术后并发症,出血(n = 4)和持续漏气(n = 2)。在平均30.7个月(±15.4个月)的随访期内,29例患者(72.5%)治愈,其余11例(27.5%)病情改善。铜绿假单胞菌感染患者(n = 3)和阻塞性气道疾病患者(n = 5)均未治愈(P分别为0.02和0.002)。

结论

对于部分单侧支气管扩张患者,根治性切除手术可安全实施,效果良好且并发症发生率低。铜绿假单胞菌感染和阻塞性气道疾病对术后治愈有不利影响。

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