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支气管扩张症的手术治疗与非手术治疗

Surgery vs non-surgical treatment for bronchiectasis.

作者信息

Corless J A, Warburton C J

机构信息

Aintree Chest Centre, University Hospital, Aintree, Aintree Chest Centre, University Hospital Aintree, Lower Lane, Liverpool, Merseyside, UK, L9 7AL.

出版信息

Cochrane Database Syst Rev. 2000;2000(4):CD002180. doi: 10.1002/14651858.CD002180.

Abstract

BACKGROUND

Standard treatment for bronchiectasis comprises postural drainage and various regimes of antibiotic therapy. If the disease is confined to localised areas of lung, surgical resection of the affected segments is often performed.

OBJECTIVES

To assess the benefit of surgical resection compared with standard ("conservative") treatment.

SEARCH STRATEGY

The Cochrane Airways Group trials register derived from MEDLINE, EMBASE and hand searching of major journals was searched using the terms [bronchiect* AND surg* OR resection OR lobect* OR pneumonect* OR segementect*].

SELECTION CRITERIA

Only randomised, controlled trials were considered

DATA COLLECTION AND ANALYSIS

The titles, abstracts and citations were independently reviewed by the two reviewers to assess potential relevance for full review. STATISTICAL CONSIDERATIONS Not applicable

MAIN RESULTS

No randomised or controlled clinical trials were found, other than case series or case-controlled studies.

REVIEWER'S CONCLUSIONS: Surgical treatment of bronchiectasis is widely used, but there appear to be no randomised controlled trials. It is not possible to provide an unbiased estimate of its benefit compared to conservative therapy.

摘要

背景

支气管扩张症的标准治疗包括体位引流和各种抗生素治疗方案。如果疾病局限于肺部的局部区域,通常会对受影响的节段进行手术切除。

目的

评估手术切除与标准(“保守”)治疗相比的益处。

检索策略

使用检索词[支气管扩张* AND 外科* 或 切除 或 肺叶切除* 或 全肺切除* 或 节段切除*]检索来自MEDLINE、EMBASE及对主要期刊进行手工检索得到的Cochrane Airways Group试验注册库。

入选标准

仅纳入随机对照试验

数据收集与分析

两名评价员独立审阅标题、摘要和引文,以评估其是否具有进行全面综述的潜在相关性。统计学考量不适用

主要结果

除病例系列或病例对照研究外,未发现随机对照临床试验。

评价员结论

支气管扩张症的手术治疗应用广泛,但似乎没有随机对照试验。与保守治疗相比,无法对其益处提供无偏估计。

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