Elkohen M
Département de médecine interne et hypertension artérielle, CHRU de Lille.
Rev Prat. 1996 May 1;46(9):1091-5.
Renal artery stenosis may be caused by either atherosclerosis or fibromuscular dysplasia, and is responsible for hypertension or renal failure. Universal screening of all hypertensive patients is not recommended because of the relatively low prevalence of the disease. A selective approach is needed. The detection of renal artery stenosis requires noninvasive tests with a high predictive value (Doppler ultrasonography, intravenous angiography, spiral CT angiography, captopril renography) in patients in whom hypertension is severe, refractory to therapy, or associated with progressive renal insufficiency. Yet, after such screening, arteriography remains the gold standard of detecting and quantifying renal artery stenosis.
肾动脉狭窄可能由动脉粥样硬化或纤维肌性发育异常引起,可导致高血压或肾衰竭。由于该病发病率相对较低,不建议对所有高血压患者进行普遍筛查。需要采取选择性方法。对于重度高血压、治疗难治性高血压或伴有进行性肾功能不全的患者,肾动脉狭窄的检测需要采用具有高预测价值的非侵入性检查(多普勒超声、静脉血管造影、螺旋CT血管造影、卡托普利肾图)。然而,经过此类筛查后,动脉造影仍是检测和量化肾动脉狭窄的金标准。