Sealy L, Mota F, Rayment N, Tatnell P, Kay J, Chain B
Department of Immunology, UCL Medical School, London, GB.
Eur J Immunol. 1996 Aug;26(8):1838-43. doi: 10.1002/eji.1830260826.
Cathepsin E is an aspartic proteinase which has been implicated in antigen processing in the class II major histocompatibility complex pathway. In this study we show that cathepsin E, measured at both the protein and message level, is up-regulated late in human B cell activation. The implications of this observation in terms of cathepsin E function are discussed.
