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[急性危及生命的心动过缓:土耳其野生蜂蜜导致的食物中毒]

[Acute life-threatening bradycardia: food poisoning by Turkish wild honey].

作者信息

von Malottki K, Wiechmann H W

机构信息

Medizinische Klinik, St. Barbara-Klinik Heessen.

出版信息

Dtsch Med Wochenschr. 1996 Jul 26;121(30):936-8. doi: 10.1055/s-2008-1043090.

DOI:10.1055/s-2008-1043090
PMID:8765701
Abstract

HISTORY AND FINDINGS

A 49-year-old Turkish man, previously well, suddenly developed severe vertigo and a feeling of retrosternal compression. The symptoms had set in within one hour of eating Turkish wild honey. The patient was in a poor general state with a heart rate of 38/min after administration of atropine by the general practitioner who had been called. Arterial blood pressure was 90/45 mmHg.

INVESTIGATION

All routine biochemical tests were normal. The electrocardiogram merely showed sinus bradycardia of 38 beats/ min.

TREATMENT AND COURSE

Under purely symptomatic treatment the heart rate and blood pressure returned to normal within 24 hours. The history of eating wild honey and typical symptoms indicated acetylandromedol poisoning.

CONCLUSION

Turkish honey from the Black Sea coast occasionally contains concentrations of acetylandromedol (formerly called andromedotoxin) high enough to cause poisoning. The substance is obtained by bees from some species of Rhododendron which they then incorporate into their honey. Typical of the poisoning are gastrointestinal symptoms and marked, even life-threatening, bradycardia and arterial hypotension.

摘要

病史与检查结果

一名49岁的土耳其男子,此前身体状况良好,突然出现严重眩晕和胸骨后压迫感。这些症状在食用土耳其野生蜂蜜后一小时内出现。患者一般状况较差,被叫来的全科医生给予阿托品后心率为38次/分钟。动脉血压为90/45 mmHg。

检查

所有常规生化检查均正常。心电图仅显示窦性心动过缓,心率为38次/分钟。

治疗与病程

在单纯对症治疗下,心率和血压在24小时内恢复正常。食用野生蜂蜜的病史和典型症状表明为乙酰基安得罗莫多尔中毒。

结论

来自黑海沿岸的土耳其蜂蜜偶尔含有足以导致中毒的高浓度乙酰基安得罗莫多尔(以前称为安得罗莫毒素)。这种物质是蜜蜂从某些杜鹃花物种中获取的,然后融入它们的蜂蜜中。中毒的典型症状是胃肠道症状以及明显的、甚至危及生命的心动过缓和动脉低血压。

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