Walkow T, Anders N, Antoni H J, Wollensak J
Augenklinik im Virchow-Klinikum, Medizinische Fakultät, Humboldt-Universität zu Berlin.
Klin Monbl Augenheilkd. 1996 May;208(5):406-9. doi: 10.1055/s-2008-1035254.
In this clinical trial the recurrence-rate after primary pterygium-excision, phototherapeutic keratectomy with the ArF:excimerlaser and local application of mitomycin C should be estimated.
Forty eyes of 38 patients underwent primary pterygium-excision using a bare-sclera technique. All patients underwent phototherapeutic keratectomy (PTK) with the ArF:excimerlaser of the wound region. Postoperative all patients were treated with mitomycin C 0.02% twice daily for four days and for 4-6 weeks with a combination of gentamycin and dexametason eye drops triple a day. Minimum follow-up was 24 month (median 41 month).
Two eyes developed a recurrence after 12 and 28 month respectively. The overall recurrence rate was 5% (corneal recurrence 2.5%). One patient developed a minute granuloma in the area of the excision. There were no other complications during the follow-up.
The excision of pterygium using the bare-sclera technique, phototherapeutic keratektomy und local application of mitomycin C 0.02% eye drops is a safe method with a low recurrence-rate. All recurrences occured after more than one year postoperatively.
在此项临床试验中，应评估原发性翼状胬肉切除术后、使用ArF准分子激光进行光治疗性角膜切削术以及局部应用丝裂霉素C后的复发率。
38例患者的40只眼采用裸巩膜技术进行原发性翼状胬肉切除术。所有患者均对伤口区域使用ArF准分子激光进行光治疗性角膜切削术（PTK）。术后所有患者每天两次使用0.02%丝裂霉素C治疗四天，并每天三次联合使用庆大霉素和地塞米松滴眼液治疗4至6周。最短随访时间为24个月（中位时间41个月）。
分别有两只眼在术后12个月和28个月出现复发。总复发率为5%（角膜复发率为2.5%）。一名患者在切除区域出现微小肉芽肿。随访期间无其他并发症。
采用裸巩膜技术切除翼状胬肉、进行光治疗性角膜切削术并局部应用0.02%丝裂霉素C滴眼液是一种安全且复发率低的方法。所有复发均发生在术后一年以上。
