Kolonbet L V
Ontogenez. 1977;8(3):269-74.
The dynamics of changes in the spectrum of lactate dehydrogenase was studied in the early pre- and postimplantation development in the CBA mice by the method of ultramicrophoresis. In the preimplantation embryos only LDH-1 was found during the first 5 days of development. The LDH-5 first appears by the 5th day of development and is preserved at all subsequent stages. The LDH spectrum of 5--7 days old embryos is represented by LDH-1 and LDH-5 and a very small amount of hybrid forms. The distribution of isozymes in the spectrum does not correspond to the binomial one. The LDH-1 is completely absent from 8--11 days old embryos and reappears in some tissues beginning from the 13th day of development. The distribution of isozymes in the LDH spectra from the 8th day of development is close to the binomial one.
采用超微量电泳法，对CBA小鼠植入前和植入后早期发育阶段乳酸脱氢酶谱变化的动力学进行了研究。在植入前胚胎发育的前5天，仅发现LDH - 1。LDH - 5在发育第5天首次出现，并在随后的所有阶段都存在。5 - 7日龄胚胎的LDH谱由LDH - 1和LDH - 5以及极少量的杂交形式组成。同工酶在谱中的分布不符合二项分布。8 - 11日龄胚胎中完全没有LDH - 1，从发育第13天开始在一些组织中重新出现。从发育第8天起，LDH谱中同工酶的分布接近二项分布。
