Gasser T C
Clinique d'Urologie, Hôpital cantonal, Bâle Suisse.
Ann Urol (Paris). 1996;30(3):124-8.
Much controversy exists as to the benefit of antimicrobial prophylaxis in transurethral surgery. Any urinary tract infection should be treated before proceeding with a transurethral operation. There is growing evidence that antimicrobial prophylaxis is also beneficial in the case of preoperatively sterile urine. A single dose or short-term prophylaxis appears to be sufficient. As newer fluoroquinolones reach very high tissue concentrations, possess a suitable antimicrobial spectrum to cover most uropathogens and may also be administered orally, these new drugs represent an attractive choice for prophylaxis in transurethral surgery.
关于抗菌药物预防在经尿道手术中的益处存在诸多争议。在进行经尿道手术前，任何尿路感染都应得到治疗。越来越多的证据表明，对于术前尿液无菌的情况，抗菌药物预防也有益处。单剂量或短期预防似乎就足够了。由于新型氟喹诺酮类药物能达到非常高的组织浓度，具有合适的抗菌谱以覆盖大多数尿路病原体，并且也可以口服给药，这些新药是经尿道手术预防的一个有吸引力的选择。
