Cremonesi A, Bucci M, Bosi S, Ricci E, Pace Palitti V, Cascino P, Martines G
Cattedra di Terapia Medica, G. D'Annunzio University, Chieti, Italy.
Riv Eur Sci Med Farmacol. 1995 Nov-Dec;17(6):209-13.
Percutaneous transluminal coronary angioplasty (PTCA) is an established technique in the management of patients with angina pectoris or acute myocardial infarction. One of the major problems related to PTCA is myocardial ischemia following balloon catheter occlusion of the coronary artery. A new device utilized in an attempt to counteract myocardial ischemia is the perfusion balloon catheter which allows passive transmission of pulsatile blood flow to the distal myocardial bed. Our purpose was to compare immediate results following traditional PTCA and autoperfusion balloon PTCA in two groups randomly assigned to receive one of the two treatments (total patients n. = 158). The results show that coronary angioplasty was successfully performed in 98.87% of patients treated with autoperfusion PTCA and in 97.10% of those treated with conventional PTCA. In the autoperfusion PTCA group we observed a lower incidence (statistically significant) of ST elevation and of minor complications. We conclude that autoperfusion balloon catheter angioplasty may be recommended for its immediate success rate with good patient tolerance and lower incidence of in-hospital complications.
经皮腔内冠状动脉成形术（PTCA）是治疗心绞痛或急性心肌梗死患者的一项成熟技术。与PTCA相关的主要问题之一是冠状动脉球囊导管闭塞后出现的心肌缺血。一种试图对抗心肌缺血的新装置是灌注球囊导管，它能使搏动性血流被动传输至远端心肌床。我们的目的是比较随机分配接受两种治疗之一（总患者数n = 158）的两组患者在传统PTCA和自动灌注球囊PTCA后的即时结果。结果显示，接受自动灌注PTCA治疗的患者中98.87%成功进行了冠状动脉成形术，接受传统PTCA治疗的患者中这一比例为97.10%。在自动灌注PTCA组，我们观察到ST段抬高和轻微并发症的发生率较低（具有统计学意义）。我们得出结论，鉴于自动灌注球囊导管血管成形术的即时成功率、良好的患者耐受性以及较低的院内并发症发生率，可推荐使用该方法。
