Luttkus A, Schäfer C, Dudenhausen J W
Abt. für Geburtsmedizin Virchow-Klinikum, Medizinische Fakultät der Humboldt Universität Berlin.
Geburtshilfe Frauenheilkd. 1996 Jun;56(6):278-82. doi: 10.1055/s-2007-1023026.
Fetal pulse oximetry (PO) requires basically continuous contact of a transcervically positioned oxisensor with fetal skin. To improve signal quality adjustments of the oxisensor may be necessary. Against this background it was our intention to find out if this intrauterine device causes an increase in fetal or maternal infectious morbidity.
We enrolled into this prospective trial 63 deliveries monitored by a blinded fetal pulse oximeter (N 400, Nellcor Inc. Pleasanton, CA) and a fetal oxisensor (FS 10; lambda = 660 + 890 nm). The control group of similar gestational age was formed by 63 chronologically following deliveries under responsibility of the same physician to reduce personal bias of obstetrical management.
While the obstetrical risk factors (non-reassuring FHR i.e.) were significantly higher in the group with PO, gestational age, number of operative deliveries, pH of umbilical cord and Apgar score ratings did not show any significant difference. The number of post partum anaemias and local or systemic infections were identical (3 in each group). Seven neonates of the PO group had to be transferred to NICU versus 12 in the control group. The duration of antibiotic treatment, mechanical ventilation or phototherapy did not differ significantly; neither did the number of neonatal infections.
In the group of fetuses monitored by fetal pulse oximetry there was no increase in fetal or maternal infectious morbidity. There was no evidence of adverse side effects which might limit the advantage of continuous oxygen saturation monitoring.
胎儿脉搏血氧饱和度测定(PO)基本上要求经宫颈放置的血氧传感器与胎儿皮肤持续接触。为提高信号质量,可能需要对血氧传感器进行调整。在此背景下,我们旨在探究这种宫内装置是否会导致胎儿或母体感染发病率增加。
我们将63例分娩纳入这项前瞻性试验,这些分娩由一台盲法胎儿脉搏血氧仪(N 400,Nellcor公司,加利福尼亚州普莱森顿)和一个胎儿血氧传感器(FS 10;波长=660 + 890纳米)进行监测。由同一医生负责的63例按时间顺序排列的后续分娩组成了孕周相似的对照组,以减少产科管理中的个人偏倚。
虽然PO组的产科危险因素(如胎儿心率异常)明显更高,但孕周、手术分娩次数、脐带血pH值和阿氏评分等级均无显著差异。产后贫血、局部或全身感染的数量相同(每组各3例)。PO组有7例新生儿需转入新生儿重症监护病房,而对照组为12例。抗生素治疗、机械通气或光疗的持续时间无显著差异;新生儿感染的数量也无差异。
在通过胎儿脉搏血氧饱和度测定监测的胎儿组中,胎儿或母体感染发病率没有增加。没有证据表明存在可能限制持续血氧饱和度监测优势的不良副作用。