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脑血管造影术后垂体卒中导致垂体功能减退和肢端肥大症消退。

Pituitary insufficiency and regression of acromegaly caused by pituitary apoplexy following cerebral angiography.

作者信息

Louwerens M, de Herder W W, Postema P T, Tanghe H L, Lamberts S W

机构信息

Department of Internal Medicine III, University Hospital Rotterdam, The Netherlands.

出版信息

Eur J Endocrinol. 1996 Jun;134(6):737-40. doi: 10.1530/eje.0.1340737.

Abstract

Pituitary apoplexy as a complication of cerebral angiography has been described in only a few case reports. Some studies have reported the clinical resolution of active acromegaly after pituitary apoplexy. We present a patient with active acromegaly due to a growth hormone (GH)-secreting pituitary macroadenoma, who developed anterior and posterior pituitary insufficiency following cerebral angiography. Furthermore, a significant reduction in tumour size was accompanied by normalization of mean 24 h in GH insulin-like growth factor I (IGF-I) and IGF binding protein 3 levels.

摘要

垂体卒中作为脑血管造影的一种并发症,仅有少数病例报告对此进行过描述。一些研究报道了垂体卒中后活动性肢端肥大症的临床缓解情况。我们报告一例因分泌生长激素(GH)的垂体大腺瘤导致的活动性肢端肥大症患者,该患者在脑血管造影后出现了垂体前叶和后叶功能减退。此外,肿瘤大小显著缩小,同时24小时平均GH、胰岛素样生长因子I(IGF-I)和IGF结合蛋白3水平恢复正常。

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