Sauer I, Ries W, Mittag M, Haustein U F
Sächs. Akademie, Wissenschaften zu Leipzig.
Z Gerontol Geriatr. 1996 May-Jun;29(3):223-32.
In 25 patients (10 male, 15 female) with systemic sclerosis aged between 28 and 79 years the biological age was determined. Alterations in the sense of "premature aging" were observed in the mean and developed stronger in male patients. They have to be counted in a greater part on the real process of disease. Compared to a healthy reference group, the expected diminishing of hand grip strength and tendon extensibility, vital capacity and partial oxygen pressure in the arteries could be confirmed. The latter correlated to an increase in rest pulse. Auditory acuity and the condition of the teeth were also reduced. Beyond that, noteworthy differences in psychological and social parameters not presumed at the beginning point to a decrease in social activities and to psychic changes. They underline the necessity of psychological counseling of the patients.
在25例年龄在28至79岁之间的系统性硬化症患者（10例男性，15例女性）中测定了生物学年龄。观察到“早衰”意义上的改变，且男性患者更为明显。这些改变在很大程度上与疾病的实际进程相关。与健康对照组相比，可证实握力、肌腱伸展性、肺活量和动脉血氧分压预期会降低。后者与静息心率增加相关。听力和牙齿状况也有所下降。除此之外，心理和社会参数方面值得注意的差异在一开始并未被推测到，这些差异表明社交活动减少和心理变化。它们强调了对患者进行心理咨询的必要性。
