成骨不全与听力损失。

Osteogenesis imperfecta and hearing loss.

作者信息

Verstreken M, Claes J, Van de Heyning P H

机构信息

Department of E.N.T., Head and Neck Surgery, University of Antwerp, Belgium.

出版信息

Acta Otorhinolaryngol Belg. 1996;50(2):91-8.

PMID:8767251

Abstract

A review of the literature of osteogenesis imperfecta (OI) and hearing loss in the last century is given. This includes the first association in 1912 by Adair-Dighton of OI with hearing loss, the triad of VAN DER HOEVE and DE KLEYN and different clinical and audiometric studies and classifications of the disease. A case report of a 14 year old patient is also included. The genetics of OI and the complexity in correlating genetics with clinical classifications is elucidated. Finally, the findings reported after middle ear surgery, the results of surgery and comparisons with otosclerosis are reviewed.

摘要

本文对上世纪关于成骨不全（OI）与听力损失的文献进行了综述。内容包括1912年阿代尔 - 戴顿首次将OI与听力损失联系起来、范德霍夫和德克莱因三联征，以及不同的临床和听力测量研究与该疾病的分类。还纳入了一名14岁患者的病例报告。阐明了OI的遗传学以及将遗传学与临床分类相关联的复杂性。最后，回顾了中耳手术后报告的研究结果、手术效果以及与耳硬化症的比较。