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[小于1500克的早产低体重儿的死亡率和发病率与分娩表现及分娩方式的关系]

[Mortality and morbidity of small premature infants (<1,500 g) in relation to presentation and delivery mode].

作者信息

Feige A, Douros A

机构信息

Frauenklinik II, Klinikum Nürnberg.

出版信息

Z Geburtshilfe Neonatol. 1996 Mar-Apr;200(2):50-5.

PMID:8767287
Abstract

It is generally recommended in the literature that small premature babies with an expected weight of < 1500 g or < 32 WOP be delivered by cesarean section. The development of some of these small babies from the uterine muscle is very time-consuming and rough. For this reason, we have established the mode of the delivery at the Nuremberg Women's Hospital on the basis of the criteria which also applies to the delivery of mature term babies irrespective of the gestational age and irrespective of their presentation. Of a total number of 10542 babies delivered, 219 babies < 1500 g in weight (2.07%) were born from 1987 to 1991. The extent to which differences in the mode of deliveries spontaneous/cesarean section result from the presentation of the small premature babies was investigates after five years. The mortality and morbidity were calculated separately for babies the weighing between 1500 g and 1000 g and for babies of < or = 999 g. Besides the perinatal and neonatal mortality, the mortality after the 29th day of life was also determined. The following parameters of early morbidity were established: 1. Respiratory distress syndrome++ (none/grade I-grade IV) 2. Intracranial hemorrhages (none/grade I-grade IV) Furthermore, the following parameters of late infant morbidity were determined after the first year of life. 1. Movement capacity (normal/hyperkinetic/apathic) 2. Development of the baby (corresponding to age/ slightly/severely retarded) Severely retarded fetuses with a gestational age of more than 32 weeks and a birth rate of < 1500 g were excluded from all calculations, so that ultimately 176 babies were included in the overall analysis. The total mortality of the children < 1500 g in weight was 14.3%, 15.7% were in the group between 1500 g and 1000 g and 25% were the mortality with regard to the presentation and the mode of delivery. The morbidity results indicate that only the group of babies between 1500 g and 1000 g in weight with breech presentation benefit from cesarean section. In the group of babies < or = 999 g, there are no differences in morbidity with regard to the mode of delivery and the presentation. The results found show that frequencies of cesarean section in excess of 40% improve neither the mortality nor the morbidity of small premature babies. The decision to carry out cesarean section is based more on individual influences and the situation in the hospital in which the delivery takes place than on mortality of the baby or the mother.

摘要

文献中普遍建议,预期体重<1500克或胎龄<32周的早产小婴儿应行剖宫产。这些小婴儿中有些从子宫肌层娩出的过程非常耗时且艰难。因此,我们在纽伦堡妇女医院根据适用于足月婴儿分娩的标准建立了分娩模式,而不论其孕周和胎位如何。在总共10542例分娩的婴儿中,1987年至1991年有219例体重<1500克(2.07%)的婴儿出生。五年后,研究了自然分娩/剖宫产分娩方式的差异在多大程度上是由早产小婴儿的胎位引起的。分别计算了体重在1500克至1000克之间的婴儿和体重≤999克的婴儿的死亡率和发病率。除围产期和新生儿死亡率外,还确定了出生后第29天之后的死亡率。确定了以下早期发病参数:1. 呼吸窘迫综合征++(无/Ⅰ-Ⅳ级)2. 颅内出血(无/Ⅰ-Ⅳ级)。此外,在婴儿出生后第一年之后确定了以下晚期发病参数:1. 运动能力(正常/运动亢进/无反应)2. 婴儿发育情况(与年龄相符/轻度/重度发育迟缓)。孕周超过32周、出生体重<1500克的严重发育迟缓胎儿被排除在所有计算之外,最终有176例婴儿纳入总体分析。体重<1500克的儿童总死亡率为14.3%,体重在1500克至1000克之间的婴儿组为15.7%,体重≤999克的婴儿组死亡率为25%,这与胎位和分娩方式有关。发病结果表明,只有体重在1500克至1000克之间、臀位的婴儿组从剖宫产中获益。在体重≤999克的婴儿组中,分娩方式和胎位在发病率方面没有差异。研究结果表明,剖宫产率超过40%既不能改善早产小婴儿的死亡率,也不能改善其发病率。剖宫产的决定更多地基于个人因素和分娩所在医院的情况,而不是婴儿或母亲的死亡率。

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