Athanasiadis S, Köhler A, Weyand G, Barthelmes L, Nafe M, Yazigi R
Abteilung für Coloproktologie, St.-Joseph-Hospital Laar, Duisburg.
Langenbecks Arch Chir. 1996;381(3):138-47. doi: 10.1007/BF00187618.
In a prospective study carried out on 78 patients with chronic constipation (31, with slow transit, 47 with obstructive defecation disorders) the evacuation function of the rectum during defecation was assessed by defecoflowmetry. These patients were compared to a control group of normal volunteers (n = 32). The following parameters were evaluated: defecation and retention volume, defecation fraction, defecation time, maximum flow, mean flow rate and time to maximum flow. As expected, there was no difference in evacuation function between the group of patients with slow transit and the control group. Significant differences, however, existed between the two types of constipation, as well as between obstructive defecation disease and controls, regarding all parameters mentioned above. Evacuation function depends neither on rectal neck pressure nor on intrarectal pressure. In patients with obstructive defecation disorders, three subgroups were discernable: one with prolonged time of defecation and satisfactory evacuation, one with prolonged time of defecation and poor evacuation, and one small group of patients who were not able to defecate. Each group is based on a different underlying pathomechanism. We conclude that changes in evacuation function of the rectum refer either to volume or to time of defecation, or to both. Changes are found only in obstructive type constipation, not in slow transit constipation. Therefore, defeconflowmetry as a dynamic procedure can be used in screening for the classification of chronic constipation.
在一项针对78例慢性便秘患者(31例慢传输型,47例出口梗阻型排便障碍)的前瞻性研究中,通过排粪造影评估排便时直肠的排空功能。将这些患者与正常志愿者对照组(n = 32)进行比较。评估了以下参数:排便量和潴留量、排便分数、排便时间、最大流速、平均流速以及达到最大流速的时间。正如预期的那样,慢传输型患者组与对照组之间的排空功能没有差异。然而,在上述所有参数方面,两种类型的便秘之间以及出口梗阻型排便障碍与对照组之间存在显著差异。排空功能既不依赖于直肠颈压力,也不依赖于直肠内压力。在出口梗阻型排便障碍患者中,可分为三个亚组:一组排便时间延长但排空良好,一组排便时间延长且排空不佳,还有一小部分患者无法排便。每组基于不同的潜在病理机制。我们得出结论,直肠排空功能的改变要么与排便量有关,要么与排便时间有关,或者与两者都有关。仅在梗阻型便秘中发现改变,而在慢传输型便秘中未发现。因此,排粪造影作为一种动态检查方法可用于慢性便秘分类的筛查。