Miller R, Duthie G S, Bartolo D C, Roe A M, Locke-Edmunds J, Mortensen N J
Department of Surgery, Bristol Royal Infirmary, UK.
Br J Surg. 1991 Jun;78(6):690-2. doi: 10.1002/bjs.1800780619.
This study examined differences in anorectal function, with particular reference to anismus, which might explain why some patients with intractable constipation have slow and others have normal whole gut transit times. Twenty-four patients were studied; 13 with slow transit (all female, median age 32 years, range 16-52 years) and 11 with normal transit (eight women, three men, median age 37 years, range 21-60 years). Videoproctography with synchronous sphincteric electromyography and anorectal manometry was performed. There were no differences between the two groups, suggesting that slow transit constipation is not secondary to any abnormality in anorectal function and may therefore be a primary disorder of colonic motility. There was no correlation between electromyographic evidence of anismus (pelvic floor contraction on defaecation) and the ability of the patient to evacute the rectum or symptoms of obstructed defaecation. Electromyography findings alone can be misleading and should be related to proctographic evidence of incomplete rectal evacuation before functional anismus can be said to be present.
本研究调查了肛门直肠功能的差异,特别关注了盆底失弛缓症,这或许可以解释为什么一些顽固性便秘患者的全肠道转运时间较慢,而另一些患者的全肠道转运时间正常。对24名患者进行了研究,其中13名肠道转运缓慢(均为女性,年龄中位数32岁,范围16 - 52岁),11名肠道转运正常(8名女性,3名男性,年龄中位数37岁,范围21 - 60岁)。进行了同步括约肌肌电图检查和肛门直肠测压的视频直肠造影。两组之间没有差异,这表明肠道转运缓慢型便秘并非继发于肛门直肠功能的任何异常,因此可能是结肠动力的原发性疾病。盆底失弛缓症的肌电图证据(排便时盆底收缩)与患者直肠排空能力或排便梗阻症状之间没有相关性。仅凭肌电图结果可能会产生误导,在能够认定存在功能性盆底失弛缓症之前,应将其与直肠排空不完全的直肠造影证据联系起来。