Becker H D
Abteilung Innere Medizin/Onkologie und Endoskopie, Thoraxklinik der LVA Baden, Heidelberg.
Ultraschall Med. 1996 Jun;17(3):106-12. doi: 10.1055/s-2007-1003156.
Since the view of the endoscopist is restricted and radiological procedures are unreliable in the diagnosis of mediastinal disease, we investigated endobronchial ultrasound in a preliminary clinical study.
Two of the systems tested, Olympus and Sonotron (CVIS), proved to be applicable after some modifications. They were tested in a phantom, in resection specimens and in 500 bronchoscopies.
In tumor staging infiltration of the bronchial wall and parabronchial structures could be assessed. Lymph nodes could be detected down to 3 mm, but not even by in vitro examination of 84 resected lymph nodes could we find reliable signs for malignancy. Infiltration of the bronchial wall and involvement of large vessels by mediastinal masses was frequently diagnosed. Involvement of the airways by vascular anomalies, pleural effusion or solid masses could be differentiated.
In view of the fact that the procedure costs around $20, it seems feasible and we are currently examining its value in a prospective study.
由于内镜医师的视野受限，且放射学检查在纵隔疾病诊断中不可靠，我们在一项初步临床研究中对支气管内超声进行了调查。
经一些改进后，测试的两个系统，即奥林巴斯和索诺特朗（CVIS），被证明是适用的。它们在模型、切除标本和500例支气管镜检查中进行了测试。
在肿瘤分期方面，可以评估支气管壁和支气管旁结构的浸润情况。可以检测到低至3毫米的淋巴结，但即使对84个切除的淋巴结进行体外检查，我们也未发现可靠的恶性征象。纵隔肿块导致的支气管壁浸润和大血管受累情况经常被诊断出来。血管异常、胸腔积液或实性肿块导致的气道受累情况可以区分。
鉴于该检查费用约为20美元，似乎是可行的，我们目前正在一项前瞻性研究中考察其价值。
