Baumgartner-Parzer S M
Klinische Abteilung für Endokrinologie und Stoffwechsel, Universität Wien.
Wien Klin Wochenschr. 1996;108(11):311-20.
Apoptosis or programmed cell death is the physiologic, natural form of cell death, exhibiting characteristic morphological and biochemical features. Apoptosis occurs upon developmental processes and represents an important defense mechanism. Defective apoptosis can result in a variety of diseases. Rapidly growing knowledge upon this mode of cell death, especially the identification of genes involved in the regulation of apoptosis raise the hope for new therapies in the treatment of cancer, autoimmune and neurodegenerative disorders, as well as viral infections.
凋亡或程序性细胞死亡是细胞死亡的生理、自然形式，呈现出特征性的形态和生化特征。凋亡发生于发育过程中，是一种重要的防御机制。凋亡缺陷可导致多种疾病。关于这种细胞死亡方式的知识迅速增长，尤其是参与凋亡调控的基因的鉴定，为癌症、自身免疫性疾病、神经退行性疾病以及病毒感染的治疗带来了新疗法的希望。
