Hahn U, Wallwiener D
Universitäts-Frauenklinik Heidelberg.
Zentralbl Gynakol. 1996;118(6):334-5.
Ovarian tumors during pregnancy are a rare event. In most cases the tumors are detected accidentially during routine examination, ultrasound or a caesarean section at term. The incidence of malignant ovarian tumors is about 1:10,000 to 1:40,000 pregnancies. Histologic subtypes and prognosis do not differ from tumors not associated with pregnancy, it seems however, that there are more lesions of borderline malignancy and of low grade. Therapy depends mostly on the age of gestation and tumor stage. Conservative surgery is recommended only in stage IA disease. Radical surgery and if necessary adjuvant therapy is recommended during the first trimester. In the third trimester a caesarean section can be followed by radical surgery, provided that there is a close cooperation between gynecologists and pediatricians. In the second trimester this regimen is possible only as an exception which includes a critical maternal risk-benefit assessment.
孕期卵巢肿瘤是一种罕见情况。多数情况下，这些肿瘤是在常规检查、超声检查或足月剖宫产时偶然发现的。恶性卵巢肿瘤在妊娠中的发生率约为1:10000至1:40000。组织学亚型和预后与非妊娠相关的肿瘤并无差异，然而，似乎交界性恶性和低级别病变更多见。治疗主要取决于妊娠孕周和肿瘤分期。仅IA期疾病推荐保守手术。孕早期推荐根治性手术，必要时进行辅助治疗。孕晚期若妇产科医生和儿科医生密切合作，可在剖宫产术后进行根治性手术。孕中期只有在包括对母亲进行关键的风险效益评估的特殊情况下才可能采用这种方案。
