• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[电离辐射作用后对溴化乙锭耐药的中国仓鼠CHLV - 79 RJK细胞有丝分裂周期的变化]

[Changes in the mitotic cycle of Chinese hamster CHLV-79 RJK cells resistant to ethidium bromide after the action of ionizing radiation].

作者信息

Kirillova T V, Spivak I M

出版信息

Tsitologiia. 1996;38(3):370-7.

PMID:8768105
Abstract

A study was made of the effect of ionizing radiation on mitotic cycle and survival of the Chinese hamster cells of two clones-CHLV-79 RJK, and its derivative Vebr-30, resistant to ethidium bromide. Ethidium bromide resistant cells were more resistant to 1) lethal effects of gamma rays (by cell survival); 2) X-rays (by cell cycle recovery after irradiation of cells in a dose of 5 Gr); 3) colcemide treatment (by accumulation of cells in G2+M phase). These data may result from damaging a certain regulatory process, which may be involved in cell response to radiation damage and in repair of predominantly sublethal and partly lethal DNA lesions as well as of cell membrane structures.

摘要

对电离辐射对两个克隆的中国仓鼠细胞(CHLV - 79 RJK及其抗溴化乙锭的衍生物Vebr - 30)的有丝分裂周期和存活的影响进行了研究。抗溴化乙锭的细胞对以下方面更具抗性:1)γ射线的致死效应(通过细胞存活情况);2)X射线(通过对5格雷剂量照射的细胞进行细胞周期恢复情况);3)秋水仙酰胺处理(通过细胞在G2 + M期的积累)。这些数据可能源于破坏了某个特定的调节过程,该过程可能参与细胞对辐射损伤的反应以及对主要是亚致死和部分致死的DNA损伤以及细胞膜结构的修复。

相似文献

1
[Changes in the mitotic cycle of Chinese hamster CHLV-79 RJK cells resistant to ethidium bromide after the action of ionizing radiation].[电离辐射作用后对溴化乙锭耐药的中国仓鼠CHLV - 79 RJK细胞有丝分裂周期的变化]
Tsitologiia. 1996;38(3):370-7.
2
[Changes in the mitotic cycle of Chinese hamster cells and the repair of radiation damage in cells following the action of ionizing radiation].[中国仓鼠细胞有丝分裂周期的变化以及电离辐射作用后细胞中辐射损伤的修复]
Tsitologiia. 1988 Dec;30(12):1432-41.
3
[The recovery of the mitotic cycle and DNA repair in Chinese hamster cells cultured on a medium with 5-bromodeoxyuridine following the action of ionizing radiation].
Tsitologiia. 1990;32(9):903-13.
4
[The karyotypic variability of Chinese hamster CHLV-79 RJK cells characterized by multiple drug resistance resulting from the amplification of the mdr gene family].[中国仓鼠CHLV - 79 RJK细胞的核型变异性,其特征为因mdr基因家族扩增导致的多药耐药性]
Tsitologiia. 1996;38(2):161-72.
5
Interaction of ionizing radiation with the topoisomerase I poison camptothecin in growing V-79 and HeLa cells.电离辐射与拓扑异构酶I抑制剂喜树碱在生长中的V - 79和HeLa细胞中的相互作用。
Cancer Res. 1994 Apr 1;54(7):1720-8.
6
[Effect of UV irradiation on the mitotic cycle of Chinese hamster cells with varying UV sensitivity. I. The time ratios after irradiation of the cells with UV light].[紫外线照射对具有不同紫外线敏感性的中国仓鼠细胞有丝分裂周期的影响。I. 紫外线照射细胞后的时间比率]
Tsitologiia. 1985 Nov;27(11):1285-91.
7
The combined effects of sublethal damage repair, cellular repopulation and redistribution in the mitotic cycle. II. The dependency of radiosensitivity parameters alpha, beta and t(0) on biological age for Chinese hamster V79 cells.亚致死损伤修复、细胞再增殖及有丝分裂周期中再分布的联合效应。II. 中国仓鼠V79细胞放射敏感性参数α、β和t(0)对生物学年龄的依赖性
Radiat Res. 1996 Apr;145(4):467-73.
8
[Effect of UV irradiation on the mitotic cycle of Chinese hamster cells with varying UV sensitivity. II. The temporal relations in blocked cell division].[紫外线照射对不同紫外线敏感性的中国仓鼠细胞有丝分裂周期的影响。II. 细胞分裂受阻中的时间关系]
Tsitologiia. 1985 Dec;27(12):1380-7.
9
[The effect of prolonged gamma irradiation at a decreasing dose rate on survivability and gene mutation induction in cultured Chinese hamster cells].[剂量率递减的长时间伽马辐射对培养的中国仓鼠细胞生存能力及基因突变诱导的影响]
Radiobiologiia. 1991 Mar-Apr;31(2):195-200.
10
Additive and supraadditive interaction between ionizing radiation and pazelliptine, a DNA topoisomerase inhibitor, in Chinese hamster V-79 fibroblasts.电离辐射与DNA拓扑异构酶抑制剂帕泽利平在中国仓鼠V-79成纤维细胞中的相加和超相加相互作用。
Cancer Res. 1991 Jun 15;51(12):3204-11.