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[The recovery of the mitotic cycle and DNA repair in Chinese hamster cells cultured on a medium with 5-bromodeoxyuridine following the action of ionizing radiation].

作者信息

Kirillova T V, Rozanov Iu M, Seregina T B, Spivak I M

出版信息

Tsitologiia. 1990;32(9):903-13.

PMID:2291243
Abstract

A correlation has been shown between a strong decrease in survival of X-irradiated CHO-K1 cells cultured with 5-BudR, a strong inhibition of recovery of DNA single-strand breaks, and an essential increase in G2-delay while progressing through the cell cycle. This strong correlation may point to the involvement of repair processes into the final radiation effect on the cell.

摘要

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