Rundback J H, Jacobs J M
Department of Radiology, Muhlenberg Hospital Center, Bethlehem, PA, USA.
Am J Kidney Dis. 1996 Aug;28(2):214-9. doi: 10.1016/s0272-6386(96)90304-2.
To evaluate the efficacy of balloon-expandable (Palmaz) stents in the treatment of atheromatous renal artery stenosis, prospective placement of stents in 24 arteries in 20 patients was performed over an 18-month period. Indications were hypertension in 18 patients and renal insufficiency (serum creatinine > 1.5 mg/dL) in 11, and all lesions failed conventional transluminal angioplasty. Technical success was achieved in 96% of cases. Hypertension benefit was noted in 77% of patients followed for 6 months (n = 13) and 67% of patients at 1 year (n = 8). Improvement in serum creatinine was seen in 71% (n = 7) and 100% (n = 3) of azotemic patients evaluated at 6 and 12 months, respectively. Six-month angiographic patency was identified in 13 of 16 treated sites. Renal artery stent placement resulted in one asymptomatic segmental branch occlusion; there were no other procedural complications. In conclusion, renal artery stent placement is a technically and clinically effective treatment for hypertension and azotemia due to renal artery stenosis.
为评估球囊扩张式（帕尔马）支架治疗动脉粥样硬化性肾动脉狭窄的疗效，在18个月期间对20例患者的24条动脉进行了前瞻性支架置入。适应症为18例患者的高血压和11例患者的肾功能不全（血清肌酐>1.5mg/dL），所有病变均未能通过传统腔内血管成形术治疗。96%的病例获得技术成功。随访6个月（n = 13）的患者中有77%和1年时（n = 8）的患者中有67%的高血压症状得到改善。分别在6个月和12个月评估时，71%（n = 7）和100%（n = 3）的氮质血症患者血清肌酐有所改善。16个治疗部位中的13个在6个月时血管造影显示通畅。肾动脉支架置入导致1例无症状节段性分支闭塞；无其他手术并发症。总之，肾动脉支架置入术是治疗肾动脉狭窄所致高血压和氮质血症的一种技术上和临床上有效的治疗方法。
