Chiappelli F, Kung M A
Laboratory of Human Oral and Molecular Immunology, UCLA School of Dentistry, USA.
Lymphology. 1995 Dec;28(4):196-207.
The health of the oral cavity is threatened by a variety of microorganisms. Impaired immune surveillance of the oral environment contributes to the development of infectious processes and tumors of the mouth. Elucidation of the physiological mechanisms that determine and control oral immune surveillance is crucial to an understanding of these oral diseases. The ability of lymphocytes to migrate is critical for successful immune surveillance. the cardinal facets of lymphocyte migration are reviewed here in the context of the oral cavity. One mechanism by which alcohol acts as an important cofactor in the onset and development of oral diseases is hypothesized to be through impaired lymphocyte migration to and from peri-oral lymphoid tissue.
口腔健康受到多种微生物的威胁。口腔环境免疫监视功能受损会促使口腔感染性疾病和肿瘤的发生。阐明决定和控制口腔免疫监视的生理机制对于理解这些口腔疾病至关重要。淋巴细胞的迁移能力对于成功的免疫监视至关重要。本文将在口腔环境中综述淋巴细胞迁移的主要方面。据推测，酒精作为口腔疾病发生和发展的重要辅助因素的一种机制是通过损害淋巴细胞在口腔周围淋巴组织的进出迁移。
