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肾综合征出血热:台湾地区首例输入性汉坦病毒感染病例。

Hemorrhagic fever with renal syndrome: first imported case of hantavirus infection in Taiwan.

作者信息

Liu J W, Lee B J, Ko W C, Chuang Y C

机构信息

Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan, ROC.

出版信息

J Formos Med Assoc. 1996 Jun;95(6):480-3.

PMID:8772056
Abstract

A patient infected with hantavirus, with resultant hemorrhagic fever with renal syndrome (HFRS), is reported. The patient was a 38-year-old man, living in Tainan, Taiwan, who had been visiting Mainland China for 3 months when he suddenly developed fever and chills, generalized myalgia, abdominal pain and petechiae on his chest. He sought treatment in Mainland China. His clinical course progressed through febrile, hypotensive, oliguria and polyuria phases. Supportive care included one course of hemodialysis. He returned to Tainan in partial defervescence. Serologic studies undertaken in Taiwan confirmed Hantaan virus infection, with one of the currently identified hantavirus strains. Hospitalization with supportive care produced further clinical improvement. Clinicians should be alert to the possibility of HFRS when examining patients who have been in endemic areas and complain of fever associated with renal dysfunction, hemorrhage or abdominal pain or both.

摘要

报告了一名感染汉坦病毒并导致肾综合征出血热(HFRS)的患者。该患者为一名38岁男性,居住在台湾台南,在中国大陆访问3个月后突然出现发热、寒战、全身肌痛、腹痛及胸部瘀点。他在中国大陆寻求治疗。其临床病程经历了发热期、低血压期、少尿期和多尿期。支持性治疗包括一个疗程的血液透析。他在体温部分消退后返回台南。在台湾进行的血清学研究证实感染了汉坦病毒,属于目前已鉴定的汉坦病毒株之一。住院并给予支持性治疗使临床症状进一步改善。临床医生在检查曾去过疫区且主诉发热伴有肾功能障碍、出血或腹痛或两者皆有的患者时,应警惕肾综合征出血热的可能性。

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