酒精相关性大细胞性贫血的胸内髓外造血的闪烁扫描诊断
Scintigraphic diagnosis of intrathoracic extramedullary hematopoiesis in alcohol-related macrocytosis.
作者信息
De Geeter F, Van Renterghem D
机构信息
Department of Nuclear Medicine, Saint John's General Hospital, Brugge, Belgium.
出版信息
J Nucl Med. 1996 Mar;37(3):473-5.
We report the scintigraphic diagnosis of thoracic extramedullary hematopoiesis in a case of alcohol-related macrocytosis. A patient with liver cirrhosis and alcohol-related macrocytosis showed multiple rounded masses in the low thoracic paraspinal region on chest radiography and CT. Whole-body scintigraphy and SPECT imaging of the thorax, after nanocolloid administration, demonstrated expansion of the bone marrow in the humeri and femora and uptake of the tracer in the mediastinal masses, establishing the diagnosis of mediastinal extramedullary hematopoiesis. Thoracic extramedullary hematopoiesis may occur in conjunction with alcohol-related macrocytosis. Scintigraphy with 99mTc-nanocolloids is a suitable noninvasive method to establish the presence of extramedullary marrow.
我们报告了一例酒精相关性大细胞性贫血患者胸段髓外造血的闪烁显像诊断。一名患有肝硬化和酒精相关性大细胞性贫血的患者在胸部X线和CT检查中显示胸段脊柱旁低区有多个圆形肿块。给予纳米胶体后进行全身闪烁显像和胸部SPECT成像，显示肱骨和股骨骨髓扩张以及纵隔肿块摄取示踪剂，从而确诊纵隔髓外造血。胸段髓外造血可能与酒精相关性大细胞性贫血同时发生。99mTc-纳米胶体闪烁显像术是确定髓外骨髓存在的一种合适的非侵入性方法。
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