Thakur S, Sharma A K, Agarwal A, Mishra S K, Bhatia E
Department of Endocrinology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow.
J Assoc Physicians India. 1995 Sep;43(9):600-1.
Association of thyroid carcinoma in thyrotoxicosis is uncommon. Preoperative diagnosis of such association is difficult. In a retrospective study of 49 operated cases of Graves' disease (GD) such an association was found in four patients. Findings of a palpable nodule, calcification and a cold nodule on scanning in Graves' disease should increase suspicion for such an association and a frozen section study should be underken in all these cases during surgery to exclude possible co-existing malignancy.
甲状腺毒症合并甲状腺癌并不常见。术前诊断这种合并情况很困难。在一项对49例接受手术的格雷夫斯病（GD）患者的回顾性研究中，发现有4例存在这种合并情况。格雷夫斯病患者出现可触及结节、钙化及扫描显示冷结节的情况，应增加对此种合并情况的怀疑，并且在所有这些病例手术期间均应进行冰冻切片检查，以排除可能并存的恶性肿瘤。
