Soriano D, Seidman D S, Mashiach S, Sela B A, Blonder J
Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Tel Hashomer, Israel.
J Perinat Med. 1996;24(2):185-9. doi: 10.1515/jpme.1996.24.2.185.
Acute intermittent porphyria (AIP) is a rare disorder of heme metabolism, which usually presents with abdominal pain, gastrointestinal symptoms and autonomic nervous system disturbances. Exacerbations first presenting during pregnancy can mimic various neuropsychiatric disorders and presents a challenging diagnosis. Furthermore, factors precipitating AIP attacks may be associated with pregnancy, including exposure to certain drugs, hyperemesis gravidum induced starvation, dieting and infection. The present case demonstrates the need for a high level of suspicion in order to diagnose this disorder in pregnancy and prevent further morbidity.
急性间歇性卟啉病（AIP）是一种罕见的血红素代谢紊乱疾病，通常表现为腹痛、胃肠道症状和自主神经系统紊乱。孕期首次发作的病情加重可能会模仿各种神经精神疾病，诊断具有挑战性。此外，引发AIP发作的因素可能与妊娠有关，包括接触某些药物、妊娠剧吐引起的饥饿、节食和感染。本病例表明，在孕期诊断这种疾病并预防进一步发病需要高度怀疑。
