Rivetz B, Bogin E, Hornstein K, Merdinger M
Res Vet Sci. 1977 May;22(3):285-91.
Chickens aged five to six weeks were inoculated with three strains of Newcastle disease virus of differing pathogenicity. The serum level of the metabolites: total protein, albumin, globulin, uric acid, total lipids, cholesterol and electrolytes: calcium, magnesium, sodium and potassium were determined. The changes in serum levels of metabolites were as follows: velogenic infection was accompanied by decrease in total protein and albumin, reduction of lipids and cholesterol and increase in uric acid. No significant changes were found in the values of these metabolites in the serum of chickens infected with mesogenic strain. Lentogenic strain caused elevation of uric acid and cholesterol. All three strains caused decrease of the level of potassium in serum.
对5至6周龄的鸡接种三种致病性不同的新城疫病毒毒株。测定了代谢物的血清水平：总蛋白、白蛋白、球蛋白、尿酸、总脂质、胆固醇以及电解质：钙、镁、钠和钾。代谢物血清水平的变化如下：速发型感染伴随着总蛋白和白蛋白的降低、脂质和胆固醇的减少以及尿酸的增加。在感染中等毒力毒株的鸡的血清中，这些代谢物的值未发现显著变化。缓发型毒株导致尿酸和胆固醇升高。所有三种毒株均导致血清钾水平降低。
