体外膜肺氧合泵驱动下的有效血液透析和血液滤过治疗高氨血症婴儿
Effective hemodialysis and hemofiltration driven by an extracorporeal membrane oxygenation pump in infants with hyperammonemia.
作者信息
Summar M, Pietsch J, Deshpande J, Schulman G
机构信息
Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA.
出版信息
J Pediatr. 1996 Mar;128(3):379-82. doi: 10.1016/s0022-3476(96)70287-1.
PMID:8774510
Abstract
Two infants with urea cycle disorders had life-threatening hyperammonemia within the first 5 days of life. Both patients were small for dates, poorly oxygenated, and hemodynamically unstable. We employed a combination of extracorporeal oxygenation and hemodialysis to provide high-flow filtration in a controlled system to rapidly detoxify both patients.
摘要
两名患有尿素循环障碍的婴儿在出生后的头5天内出现了危及生命的高氨血症。两名患者均小于胎龄、氧合不良且血流动力学不稳定。我们采用体外氧合和血液透析相结合的方法，在一个可控系统中进行高流量过滤，以迅速为两名患者解毒。
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