Korenberg E I
Gamaleya Institute for Epidemiology and Microbiology, Russian Academy of Medical Sciences, Moscow, Russia.
Folia Parasitol (Praha). 1995;42(4):307-12.
To rank variables affecting risk of human disease due to tick-borne encephalitis (TBE) virus in the Russian Far East, we compared annual changes in (1) frequency of human contact with vector ticks, (2) prevalence of infection in the tick population and (3) quantity of virus present infected ticks. Sites were sampled uniformly over a 4-year period in a forested region where Ixodes persulcatus serves as the principle vector. The questing density of ticks on vegetation remained relatively constant during the course of this study. The frequency of contacts of the local human population with ticks carrying different doses of the TBE virus was changeable. The rate of TBE infection of humans in the study site corresponded to that of human contacts with highly infected ticks. The density of highly infected ticks represents the principal parameter for determining potential epidemiological significance of a natural TBE focus.
为了对俄罗斯远东地区蜱传脑炎（TBE）病毒所致人类疾病风险的影响变量进行排序，我们比较了以下方面的年度变化：（1）人类与媒介蜱的接触频率；（2）蜱种群中的感染率；（3）受感染蜱体内的病毒量。在一个以全沟硬蜱为主要媒介的森林地区，在4年时间内对各地点进行了统一采样。在本研究过程中，植被上蜱的搜索密度保持相对恒定。当地人群与携带不同剂量TBE病毒的蜱的接触频率是可变的。研究地点人类的TBE感染率与人类接触高感染蜱的比率相对应。高感染蜱的密度是确定自然TBE疫源地潜在流行病学意义的主要参数。
