Miller F R, Wanamaker J R, Lavertu P, Wood B G
Department of Otolaryngology and Communicative Disorders, Cleveland Clinic Foundation, Ohio, 44195, USA.
Head Neck. 1996 Jan-Feb;18(1):67-77. doi: 10.1002/(SICI)1097-0347(199601/02)18:1<67::AID-HED9>3.0.CO;2-X.
The purpose of this study was to evaluate our experience with the diagnosis and management of tumors of the parapharyngeal space (PPS), with particular emphasis on the evolving role of magnetic resonance imaging (MRI).
A case series review of 51 patients with parapharyngeal tumors who underwent surgical excision between 1980 and 1992 were analyzed with regard to presenting signs and symptoms, histologic diagnosis, imaging technique (computed tomography [CT] versus MRI), surgical approach, and outcome.
Fifty-one patients underwent surgical excision of a parapharyngeal tumor of which the vast majority (78%) were benign neoplasms. Compared with benign neoplasms, the malignant tumors were much more likely to be associated with pain, trismus, and a cranial nerve deficit. MRI was able to locate the tumor in 20 of 21 patients (95%), while CT was able to localize the tumor in 32 of 38 patients (84%).
MRI, because of its superior soft-tissue resolution and ability to provide imaging in multiple planes, is the imaging modality of choice to diagnose neoplasms of the parapharyngeal space. Because most of these tumors are benign, MRI allows the surgeon to select the surgical approach with the least morbidity.
本研究旨在评估我们在咽旁间隙（PPS）肿瘤诊断和治疗方面的经验，特别强调磁共振成像（MRI）不断演变的作用。
对1980年至1992年间接受手术切除的51例咽旁肿瘤患者进行病例系列回顾，分析其临床表现、组织学诊断、成像技术（计算机断层扫描[CT]与MRI）、手术方法及结果。
51例患者接受了咽旁肿瘤的手术切除，其中绝大多数（78%）为良性肿瘤。与良性肿瘤相比，恶性肿瘤更易伴有疼痛、牙关紧闭和颅神经缺损。MRI能够在21例患者中的20例（95%）定位肿瘤，而CT能够在38例患者中的32例（84%）定位肿瘤。
由于MRI具有卓越的软组织分辨率以及在多个平面提供成像的能力，它是诊断咽旁间隙肿瘤的首选成像方式。由于这些肿瘤大多为良性，MRI使外科医生能够选择发病率最低的手术方法。
