Kashiyama T, Suzuki A, Mizuguchi K
Department of Internal Medicine, Tokyo Metropolitan Okubo Hospital.
Intern Med. 1995 Nov;34(11):1110-3. doi: 10.2169/internalmedicine.34.1110.
Wegener's granulomatosis (WG) is a disease of unknown origin characterized by necrotizing granulomas of both the upper and lower respiratory tracts and glomerulonephritis. A 62-year-old woman presenting unusual neurological manifestations is reported. The patient suffered from palsies of multiple cranial nerves without manifestation of respiratory tracts in the initial clinical course. Seven years after the onset, pulmonary consolidations appeared on the chest X-ray study. A diagnosis was made by a needle biopsy of the lung. Palsies of cranial nerves suspected to be due to meningeal involvement of WG. During the entire clinical course, no finding of glomerulonephritis was observed.
韦格纳肉芽肿病（WG）是一种病因不明的疾病，其特征为上、下呼吸道的坏死性肉芽肿和肾小球肾炎。本文报告了一名出现异常神经表现的62岁女性。该患者在最初的临床病程中出现多条颅神经麻痹，无呼吸道表现。发病7年后，胸部X线检查显示肺部实变。通过肺穿刺活检做出诊断。怀疑颅神经麻痹是由于WG的脑膜受累所致。在整个临床病程中，未观察到肾小球肾炎的表现。
