Kümmerling S, Schubert J
Department of Urology, Friedrich Schiller University of Jena, F. R. Germany.
Int Urol Nephrol. 1995;27(5):629-37. doi: 10.1007/BF02564751.
There are still diverse management options in Peyronie's disease, due to its unknown aetiology, progression or remission. Types, extent and duration of operative management in this disease are subject of controversial discussion. We did complex investigations in 132 patients revealing the following items. Diagnostic tests should include both history and physical examination and comparative X-ray and ultrasound investigations. CT is the best method to differentiate pathological lesions in the tunica albuginea. X-ray (xerography) examination demonstrates calcification of the plaque. Papaverin-hydrochloride injection is a valid method to check the extension of concomitant erectile dysfunction and shows the angulation of the penis. Plaque excision and grafting with various materials were used initially with disappointing results (15 patients, only 20% good results). Modified corporal plication has been used subsequently with good results (54 patients, follow-up 3 years, 90% good results). Implantation of penile prosthesis must be evaluated individually.
由于佩罗尼氏病病因不明、病情进展或缓解情况未知，目前仍有多种治疗方案。该病手术治疗的类型、范围和持续时间是备受争议的话题。我们对132例患者进行了综合检查，发现以下情况。诊断测试应包括病史、体格检查以及X线和超声对比检查。CT是鉴别白膜病理性病变的最佳方法。X线（干板照相）检查可显示斑块钙化。注射盐酸罂粟碱是检查伴发性勃起功能障碍程度并显示阴茎弯曲度的有效方法。最初采用斑块切除并使用各种材料进行移植，结果令人失望（15例患者，仅有20%效果良好）。随后采用改良的海绵体折叠术，效果良好（54例患者，随访3年，90%效果良好）。阴茎假体植入必须个体化评估。
