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使用合成代谢雄激素类固醇的健美运动员体内的脂蛋白(a)和胆固醇

Lipoprotein (a) and cholesterol in body builders using anabolic androgenic steroids.

作者信息

Cohen L I, Hartford C G, Rogers G G

机构信息

Department of Physiology, University of the Witwatersrand Medical School, Parktown, Johannesburg, South Africa.

出版信息

Med Sci Sports Exerc. 1996 Feb;28(2):176-9. doi: 10.1097/00005768-199602000-00004.

DOI:10.1097/00005768-199602000-00004
PMID:8775151
Abstract

We examined the influence of self-administered anabolic androgenic steroids (AAS) on the lipogram of male body builders. Serum lipoprotein (a) (Lp(a)), total cholesterol, low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) levels were measured in 10 experimental and 8 control male competitive body builders. The proportion of subjects with serum Lp(a) levels above 30 mg.dl-1 was significantly lower in the AAS group than the non-AAS group. HDL-C levels were significantly lower and LDL-C levels significantly higher in the AAS group than the non-AAS group. These data suggest that AAS in male body builders have a beneficial effect on serum Lp(a) levels but reduce the HDL-C:LDL-C ratio.

摘要

我们研究了自行使用合成代谢雄激素类固醇(AAS)对男性健美运动员血脂谱的影响。对10名实验对象和8名对照男性竞技健美运动员测量了血清脂蛋白(a)[Lp(a)]、总胆固醇、低密度脂蛋白胆固醇(LDL-C)和高密度脂蛋白胆固醇(HDL-C)水平。AAS组血清Lp(a)水平高于30mg·dl⁻¹的受试者比例显著低于非AAS组。AAS组的HDL-C水平显著低于非AAS组,而LDL-C水平显著高于非AAS组。这些数据表明,男性健美运动员使用AAS对血清Lp(a)水平有有益影响,但会降低HDL-C与LDL-C的比值。

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