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[猴子短期记忆机制中的同步过程:胆碱能和谷氨酰胺能皮质结构的参与]

[Synchronization processes in the mechanisms of short-term memory in monkeys: the participation of cholinergic and glutaminergic cortical structures].

作者信息

Dudkin K N, Kruchinin V K, Chueva I V

机构信息

Pavlov Institute of Physiology of the Russian Acad. Sci., St. Petersburg.

出版信息

Fiziol Zh Im I M Sechenova. 1995 Aug;81(8):128-34.

PMID:8775446
Abstract

Administration of amysil blocking M-cholinoreceptors, and APV the duration of short-term storing of information was decreased whereas the motor response time increased. This was followed by a considerable desynchronisation of the unit activity. The NMDA and APB improved the characteristics of the short-term memory. The role of synchronisation of the information processes in the short-term memory mechanisms and participation of cholinergic and glutamatergic systems in them, are discussed.

摘要

给予阻断M胆碱能受体的淀粉样蛋白以及APV后,信息短期存储的持续时间缩短,而运动反应时间延长。随后单位活动出现明显去同步化。NMDA和APB改善了短期记忆的特征。本文讨论了信息过程同步在短期记忆机制中的作用以及胆碱能和谷氨酸能系统在其中的参与情况。

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