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卟啉诱导：5αH和5βH类固醇对鸡胚肝细胞的等效作用。

Porphyrin induction: equivalent effects of 5alphaH and 5betaH steroids in chick embryo liver cells.

作者信息

Stephens J K, Fischer P W, Marks G S

出版信息

Science. 1977 Aug 12;197(4304):659-60. doi: 10.1126/science.877578.

DOI:10.1126/science.877578
PMID:877578
Abstract

The 5alphaH (A : B trans) and 5betaH (A : B cis) steroids are equipotent in inducing delta-aminolevulinic acid synthetase and porphyrin accumulation in chick embryo liver cells maintained in serum-free culture medium. Thus there is no specific steric requirement for porphyrin-inducing activity in steroids.

摘要

5αH（A:B反式）和5βH（A:B顺式）类固醇在无血清培养基中培养的鸡胚肝细胞中，诱导δ-氨基乙酰丙酸合成酶和卟啉积累方面具有同等效力。因此，类固醇中诱导卟啉的活性没有特定的空间要求。

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Science. 1977 Aug 12;197(4304):659-60. doi: 10.1126/science.877578.
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