Gómez-Arnau J, Planas A, Lora-Tamayo J I, Martínez M V
Servicio de Anestesia-Reanimación, Hospital Puerta de Hierro, Madrid.
Rev Esp Cardiol. 1995;48 Suppl 7:60-4.
Right ventricular dysfunction is a common clinical event after heart transplantation. The major cause is the failure of right ventricle (RV) to adapt to the pulmonary hypertension (PH) secondary to chronic heart failure. Nevertheless, this dysfunction is usually transient owing to the reversibility of PH, the nature of which is mainly passive. Therefore, it is particularly important to perform a preoperative hemodynamic study to identify those cases in which PH is a permanent component, a situation that excessively increases the risk of postoperative RV failure. Once this occurs, the treatment is complex. The available therapeutic measures include the use of vasodilators such as prostaglandin E1 and nitric oxide.
右心室功能障碍是心脏移植术后常见的临床情况。主要原因是右心室(RV)无法适应继发于慢性心力衰竭的肺动脉高压(PH)。然而,由于PH的可逆性(其本质主要是被动性的),这种功能障碍通常是短暂的。因此,术前进行血流动力学研究以识别那些PH为永久性成分的病例尤为重要,这种情况会过度增加术后右心室衰竭的风险。一旦发生这种情况,治疗就很复杂。可用的治疗措施包括使用血管扩张剂,如前列腺素E1和一氧化氮。