du Plessis A J
Department of Neurology, Children's Hospital, Boston, MA 02115, USA.
Curr Opin Pediatr. 1995 Dec;7(6):632-9. doi: 10.1097/00008480-199512000-00002.
With the advent of near-infrared spectroscopy (NIRS), it has become possible for the first time to make continuous measurements of in vivo cerebral oxygenation and hemodynamic changes at the bedside, in the intensive care unit, and in the operating room. NIRS has shown immense potential as a noninvasive technique for monitoring real-time cerebrovascular and oxygenation changes in the critically ill child. To date, clinical applications of the technique have included cerebral measurements in the intrapartum fetus, the high-risk newborn, and the infant undergoing extracorporeal membrane oxygenation and hypothermic cardiac surgery. Despite these advances in the clinical application of the NIRS technique, several basic controversies persist and are the focus of intense research in the area. This review provides an update on recent clinical studies using NIRS and outlines the likely future directions of the technique.
随着近红外光谱技术（NIRS）的出现，首次有可能在床边、重症监护病房和手术室对活体大脑的氧合作用和血流动力学变化进行连续测量。NIRS作为一种用于监测危重病患儿实时脑血管和氧合变化的无创技术，已显示出巨大的潜力。迄今为止，该技术的临床应用包括对产时胎儿、高危新生儿以及接受体外膜肺氧合和低温心脏手术的婴儿进行脑部测量。尽管NIRS技术在临床应用方面取得了这些进展，但仍存在一些基本争议，这些争议是该领域深入研究的焦点。本综述提供了使用NIRS的近期临床研究的最新情况，并概述了该技术可能的未来发展方向。
